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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
10
Human Site:
T265
Identified Species:
18.33
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
T265
S
L
R
Q
T
N
K
T
K
Q
S
C
P
F
G
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
T265
S
L
R
Q
T
N
K
T
K
Q
S
C
P
F
G
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
N226
L
G
H
L
Q
N
R
N
N
S
C
D
S
R
G
Dog
Lupus familis
XP_539016
855
96614
N263
R
N
S
L
K
Q
T
N
K
A
K
R
S
C
P
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
A261
P
F
K
Q
T
H
A
A
K
R
S
C
P
F
G
Rat
Rattus norvegicus
NP_001101642
835
94323
P243
I
L
Y
G
E
N
M
P
P
K
D
A
E
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
P268
P
L
K
P
F
S
K
P
K
L
A
C
P
F
G
Chicken
Gallus gallus
XP_419867
879
99691
S269
P
L
R
P
L
N
K
S
N
Q
A
C
P
F
G
Frog
Xenopus laevis
NP_001082090
882
99060
S267
R
K
P
L
L
N
M
S
A
K
T
C
P
L
G
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
I327
D
I
E
E
G
H
T
I
T
A
L
L
N
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
L240
A
M
V
V
Q
D
Q
L
H
Q
L
R
N
F
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
N225
G
Q
L
G
E
F
P
N
F
L
N
Q
P
R
T
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
R212
Q
T
N
F
K
E
R
R
E
N
T
D
Y
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
53.3
13.3
N.A.
46.6
60
26.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
6.6
N.A.
73.3
20
N.A.
66.6
73.3
46.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
40
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
8
8
16
16
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
47
0
8
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
0
8
16
0
8
0
% D
% Glu:
0
0
8
8
16
8
0
0
8
0
0
0
8
0
0
% E
% Phe:
0
8
0
8
8
8
0
0
8
0
0
0
0
47
0
% F
% Gly:
8
8
0
16
8
0
0
0
0
0
0
0
0
0
54
% G
% His:
0
0
8
0
0
16
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
8
16
0
16
0
31
0
39
16
8
0
0
0
0
% K
% Leu:
8
39
8
24
16
0
0
8
0
16
16
8
0
8
8
% L
% Met:
0
8
0
0
0
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
47
0
24
16
8
8
0
16
0
0
% N
% Pro:
24
0
8
16
0
0
8
16
8
0
0
0
54
0
8
% P
% Gln:
8
8
0
24
16
8
8
0
0
31
0
8
0
0
0
% Q
% Arg:
16
0
24
0
0
0
16
8
0
8
0
16
0
24
0
% R
% Ser:
16
0
8
0
0
8
0
16
0
8
24
0
16
0
16
% S
% Thr:
0
8
0
0
24
0
16
16
8
0
16
0
0
0
8
% T
% Val:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _